Ursodeoxycholic acid 128-13-2 Sistimi ea tšilo ea lijo Cholagogic
Tefo:T/T, L/C
Tšimoloho ea Sehlahisoa:China
Boema-kepe:Beijing/Shanghai/Hangzhou
Bokhoni ba tlhahiso:2000kg / khoeli
Odara(MOQ):25kg
Lead time:3 Matsatsi a ho sebetsa
Boemo ba polokelo:E bolokiloe sebakeng se pholileng, se omileng, mocheso oa kamore.
Lintho tsa sephutheloana:moropa
Boholo ba sephutheloana:25kg/moropa
Lintlha tsa polokeho:Eseng thepa e kotsi
Selelekela
Ursodeoxycholic acid (UDCA), eo hape e tsejoang e le ursodiol, ke bile acid ea bobeli, e hlahisoang ho batho le mefuta e meng e mengata ho tsoa ho metabolism ke libaktheria tsa mala.E entsoe ka har'a sebete mefuteng e meng, 'me e ile ea qala ho tsejoa ka har'a bile ea bere, e leng tšimoloho ea lebitso la eona la Ursus.Ka mokhoa o hloekisitsoeng, e 'nile ea sebelisoa ho phekola kapa ho thibela mafu a' maloa a sebete kapa li-bile ducts.
UDCA e 'nile ea sebelisoa e le phekolo ea meriana ho lefu la gallstone (cholelithiasis) le bakeng sa biliary sludge.UDCA e thusa ho fokotsa k'holeseterole e tletseng bile 'me e lebisa ho qhibiliha butle-butle ha li-gallstones tse nang le k'holeseterole e ngata.
UDCA e ka fanoa ka mor'a opereishene ea bariatric ho thibela cholelithiasis, e atisang ho hlaha ka lebaka la tahlehelo ea boima ba 'mele e hlahisang biliary cholesterol oversaturation le biliary dyskinesia secondary hormonal changes.
Tlhaloso (EP10)
| Ntho | Tlhaloso |
| Ponahalo | Phofo e tšoeu kapa e batlang e le tšoeu |
| Solubility | Ha e qhibilihe ka metsing, e qhibiliha ka bolokolohi ka har'a ethanol (96%), e qhibiliha hanyane ka har'a acetone, hoo e batlang e sa qhibilihe ka har'a methylene chloride. |
| Sebaka se qhibilihang | 202-204 ℃ |
| Boitsebiso | Mofuta o tšoanang oa IR joalo ka ursodeoxycholic acid CRS |
| Sebaka sa mantlha sa chromatogram se fumanoeng ka tharollo ea teko (b) se tšoana ka boemo, 'mala le boholo le sebaka sa mantlha sa chromatogram se fumanoeng ka tharollo ea litšupiso (a). | |
| Ho emisoa ho fumanoeng ke botala bo botala. | |
| Potoloho e khethehileng ea optical | +58.0~+62.0° |
| Ho se hloeke C | Lithocholic acid ≤ 0.1% |
| Lintho tse amanang le tsona (HPLC) | litšila A: chenodeoxycholic acid ≤ 1.0% |
| litšila tse sa hlalosoang ≤ 0.1% | |
| kakaretso ≤ 1.5% | |
| Litšepe tse boima | ICH Q3D |
| Tahlehelo ka ho omisa | ≤ 1.0% |
| Molora o nang le sulphated | ≤ 0.1% |
| Tlhahlobo | 99.0%~101% (Lintho tse omisitsoeng) |
| Li-solvents tse setseng | Acetone ≤ 5000 ppm Ethyl acetate ≤ 5000 ppm Isopropanol ≤ 5000 ppm Ethanol ≤ 5000 ppm |
| Liteko tsa Microbiological | Kakaretso ea palo ea likokoana-hloko tsa aerobic ≤ 10³CFU/g Kakaretso ea litomoso le hlobo li baloa ≤ 10²CFU/g Escherichia coli: Ha e eo ka 1 g Salmonella: Ha e eo ka 10 g |
| Matlotlo a eketsehileng | |
| Kabo ea boholo ba karolo | 100% pass number 180 sieve (100% feta 80 mesh sieve) |
