Li-tubes tsa laboratori

Sehlahisoa

Rivaroxaban 366789-02-8 Tsamaiso ea mali e sireletsa Antithrombosis

Tlhaloso e Khutšoanyane:

Mantsoe a tšoanang:5-Chloro-N-[[(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)phenyl]-5-oxazolidinyl]methyl]-2-thiophenecarboxamide

Nomoro ea CAS:366789-02-8

Boleng:EP

Foromo ea molek'hule:C19H18ClN3O5S

Boima ba Foromo:435.88


Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Tefo:T/T, L/C
Tšimoloho ea Sehlahisoa:China
Boema-kepe:Beijing/Shanghai/Hangzhou
Bokhoni ba tlhahiso:200kg / khoeli
Odara(MOQ):25kg
Lead time:3 Matsatsi a ho sebetsa
Boemo ba polokelo:E bolokiloe sebakeng se pholileng, se omileng, mocheso oa kamore.
Lintho tsa sephutheloana:moropa
Boholo ba sephutheloana:25kg / moropa
Lintlha tsa polokeho:Eseng thepa e kotsi

Rivaroxaban

Selelekela

Rivaroxaban, ke meriana ea anticoagulant (e fokolang mali).E sebelisoa ho batho ba baholo ba nang le nonvalvular atrial fibrillation (ntle le atrial fibrillation ka lebaka la lefu la pelo la rheumatic valvular, le atrial fibrillation ka mor'a ho nkeloa sebaka ke valve ea pelo) ho fokotsa kotsi ea stroke le systemic embolism.
Rivaroxaban, e sebelisetsoa ho phekola le ho thibela mali.
Rivaroxaban, e sebelisoa f bakeng sa bakuli ba baholo ba etsoang opereishene e khethehileng ea letheka kapa lengole ho thibela venous thrombosis.

Tlhaloso (EP)

Ntho

Tlhaloso

Ponahalo

Phofo e tšoeu kapa e mosehla

Solubility

Ha e qhibilihe ka metsing, e qhibiliha ka bolokolohi ho DMSO, hoo e batlang e sa qhibilihe ka har'a anhydrous ethanol le heptanes.

Boitsebiso

IR: Spectrum e lokela ho lumellana le WS

 

HPLC-RT ea sampole tlasa tlhahlobo ea bohloeki ea enantiometric e lokela ho lumellana le ea WS.

Metsi ≤0.5%

Molora oa sulphate

≤0.1%

Tahlehelo ka ho omisa

≤0.5%
Litšepe tse boima ≤20ppm

Enantionmer

Tšilafalo A: ≤0.4%

Mokelikeli o setseng

Ethanol: ≤5000ppm

Ethyl acetate: ≤5000ppm

Acetone: ≤5000ppm

N, N-Dimethylformamide: ≤880ppm

Methylene chloride: ≤600ppm

Benzene: ≤2ppm

Ntho e amanang le yona

Tšilafalo B: ≤0.10%

Tšilafalo D: ≤0.10%

Tšilafalo E: ≤0.10%

Tšilafalo F: ≤0.10%

Tšilafalo G: ≤0.10%

Tšilafalo H: ≤0.10%

Tšilafalo ea I: ≤0.10%

Impurity J: ≤0.10%

RVB-4-NJSH: ≤0.10%

RVB-ZA: ≤0.10%

RVB-BAM: ≤0.10%

RVB-ZC: ≤0.10%

RVB-HBY: ≤75ppm

Tšilafalo efe kapa efe e sa tsejoeng: ≤0.10%

Ho se hloeke hohle: ≤0.3%

Kabo ea boholo ba karolo

D10:/

D50:/

D90:/

Tlhahlobo

(ntho e se nang metsi)

98.0-102.0

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