Tacrolimus monohydrate 109581-93-3 Antibiotic
Tefo:T/T, L/C
Tšimoloho ea Sehlahisoa:China
Boema-kepe:Beijing/Shanghai/Hangzhou
Bokhoni ba tlhahiso:1kg/khoeli
Odara(MOQ):1g
Lead time:3 Matsatsi a ho sebetsa
Boemo ba polokelo:E bolokiloe sebakeng se pholileng, se omileng, mocheso oa kamore.
Lintho tsa sephutheloana:vial, botlolo
Boholo ba sephutheloana:1g/vial, 5/vial, 10g/vial, 50g/botlolo, 500g/botlolo
Lintlha tsa polokeho:UN 2811 6.1/PG 3
Selelekela
Tacrolimus, ke lithethefatsi tse thibelang ho itšireletsa mafung.Ka mor'a ho fetisoa ha setho sa allogeneic, kotsi ea ho hana litho tsa 'mele e leka-lekane.Ho fokotsa kotsi ea ho lahloa ha litho tsa 'mele, tacrolimus e fanoa.Setlhare sena se ka boela sa rekisoa e le meriana ea li-topical ho phekola mafu a T-cell-mediated a kang eczema le psoriasis.E ka sebelisoa ho phekola lefu la mahlo a omileng ho likatse le lintja.
Tacrolimus e thibela calcineurin, e amehang tlhahisong ea interleukin-2, molek'hule e khothalletsang nts'etsopele le ho ata ha lisele tsa T, e le karolo ea 'mele o ithutoang (kapa o fetohang) oa ho itšireletsa mafung.
Tlhaloso (USP43)
| Ntho | Tlhaloso |
| Ponahalo | Phofo ea kristale e tšoeu kapa e batlang e le tšoeu |
| Boitsebiso | IR, HPLC |
| Solubility | E qhibiliha haholo ka methanol, e qhibiliha ka bolokolohi ho N, N dimethylformamide le joala, hoo e batlang e le ka har'a metsi. |
| Masalla ha a tuka | ≤0.10 % |
| Litšila tsa 'mele (mokhoa-2) | Ascomycin 19-epimer ≤0.10 % |
| Ascomycin ≤0.50% | |
| Desmethyl tacrolimus ≤0.10% | |
| Tacrolimus 8-epimer ≤0.15% | |
| Tacrolimus 8-propyl analoge ≤0.15% | |
| Ho se hloeke ho sa tsejoeng -I ≤0.10 % | |
| Ho se hloeke ho sa tsejoeng -II ≤0.10 % | |
| Ho se hloeke ho sa tsejoeng -III ≤0.10 % | |
| Kakaretso ea litšila ≤1.00 % | |
| Ho potoloha ha Optical (ho ea kamoo ho leng ka teng) (10mg/ml ho N,Ndimethylformamide) | -110.0 ° ~ -115.0° |
| Likahare tsa metsi (ka KF) | ≤4.0% |
| Li-solvents tse setseng (ka GC) | Acetone ≤1000ppm (Ka tlung) |
| Di-isopropyl ether ≤100ppm (Ka tlung) | |
| Ethyl ether ≤5000ppm | |
| Acetonitrile ≤410ppm | |
| Toluene ≤890ppm | |
| Hexane ≤290ppm | |
| Teko ea likokoana-hloko (ka tlung) | Kakaretso ea palo ea likokoana-hloko tsa aerobic ≤100cfu/gm |
| Kakaretso ea tomoso le hlobo palo ≤10cfu/gm | |
| Likokoana-hloko tse boletsoeng (Likokoana-hloko) (E.coil, salmonella sps., S.aureus. Pseudomonas aeruginosa) ha ea lokela ho ba teng | |
| Assay (ka HPLC) (ka motheo oa anhydrous le solvent free) | 98%~102% |
