Orlistat 96829-58-2 Antiobesity Diet supplement
Tefo:T/T, L/C
Tšimoloho ea Sehlahisoa:China
Boema-kepe:Beijing/Shanghai/Hangzhou
Bokhoni ba tlhahiso:800kg / khoeli
Odara(MOQ):25kg
Lead time:3 Matsatsi a ho sebetsa
Boemo ba polokelo:E bolokiloe sebakeng se pholileng, se omileng, mocheso oa kamore.
Lintho tsa sephutheloana:moropa
Boholo ba sephutheloana:25kg / moropa
Lintlha tsa polokeho:Eseng thepa e kotsi
Selelekela
Orlistat ke inhibitor e sebetsang ka nako e telele ebile e matla ka ho khetheha ka mpeng ea lipase inhibitor.Ke phofo e tšoeu kapa e batlang e le tšoeu mochesong oa kamore, e sa qhibiliheng ka metsing, e qhibilihang ka chloroform, 'me e qhibiliha habonolo ka ethanol.E thibela enzyme ka ho theha maqhama a covalent le libaka tse sebetsang tsa serine tsa gastric lipase le pancreatic lipase ka mpeng le mala a manyane.
Orlistat ke mofuta oa lithethefatsi tse theolang boima ba 'mele lipase inhibitor.Ke hydrated derivative ea lipstatin, e ka fokotsang ho monya mafura a lijo le ho fokotsa boima ba 'mele.Sehlahisoa sena se na le inhibition e matla le e khethollang ea gastric lipase le pancreatic lipase, ha e na phello ho li-enzyme tse ling tsa tšilo ea lijo (amylase, trypsin, chymotrypsin) le phospholipase, mme ha e ame ho monya ha lik'habohaedreite, liprotheine le phospholipids.E thibela enzyme haholo-holo ka ho tlama li-covalent le masala a serine libakeng tse sebetsang tsa gastric lipase le pancreatic lipase ka har'a pampitšana ea gastrointestinal, e thibela hydrolysis ea triacylglycerol, e fokotsa ho kenngoa ha monoglyceride le mafura a mafura a mahala, kahoo e laola boima ba 'mele.Setlhare ha se kenelle ka mpeng, 'me thibelo ea lipase e ka khutlisoa.
Sehlahisoa sena se boetse se na le mosebetsi oa ho laola lipids tsa mali.E ka fokotsa triglyceride le low-density lipoprotein cholesterol serum ea bakuli ba batenya le ho eketsa karo-karolelano ea high-density lipoprotein ho low-density lipoprotein.
Ha orlistat e kopantsoe le lijo tse nang le khalori e tlase, e loketse kalafo ea nako e telele ea batho ba batenya le ba batenya haholo, ho kenyeletsoa ba nang le maemo a kotsi a amanang le botenya.E na le ts'ebetso ea nako e telele ea ho laola boima ba 'mele joalo ka ho theola boima ba' mele, ho boloka boima ba 'mele le ho thibela ho khutla hape.Tleliniki e bontša ka ho hlaka hore ts'ebetso ea ho laola boima ba 'mele e bohlokoa haholo bakeng sa ts'ebeliso ea nako e telele ha u e-na le lijo kapa ka mor'a hora e le' ngoe ea lijo.
Orlistat e ka fokotsa sekhahla sa maemo a kotsi a amanang le botenya le mafu a mang a amanang le botenya, ho kenyelletsa hypercholesterolemia, mofuta oa lefu la tsoekere la mofuta oa II, ho se mamelle tsoekere, hyperinsulinemia, khatello ea mali, le ho fokotsa mafura lithong tsa 'mele.
Tlhaloso (USP42)
| Ntho | Tlhaloso |
| Boitsebiso | HPLC, IR |
| Potoloho e khethehileng ea optical | -48.0°~-51.0° |
| Likahare tsa metsi | ≤0.2% |
| Lintho tse amanang le tsona I | Motsoako o amanang le Orlistat A ≤0.2% |
| Lintho tse amanang le tsona II | Motsoako o amanang le Orlistat B ≤0.05% |
| Lintho tse amanang III
| Formylleucine ≤0.2% |
| Motsoako o amanang le Orlistat C ≤0.05% | |
| Orlistat bula lesale epimer ≤0.2% | |
| D-Leucine orlistat ≤0.2% | |
| Ho se hloeke ha motho ka mong ho sa tsejoeng ≤0.1% | |
| Lintho tse amanang IV | Motsoako o amanang le Orlistat D ≤0.2% |
| Orlistat bula ring amide ≤0.1% | |
| Lintho tse amanang le V | Orlistat e amanang le motsoako E ≤0.2% |
| Kakaretso ea litšila (I ho isa ho V) | ≤1.0% |
| Li-solvents tse setseng | Methanol ≤0.3% |
| EtOAc ≤0.5% | |
| n-Heptane ≤0.5% | |
| Masalla ha a tuka | ≤0.1% |
| Limetale tse boima joalo ka Pb | ≤20ppm |
| Tlhahlobo ea HPLC | 98.0% ~ 101.5% (motheong oa anhydrous, o se nang solvent) |
