Alprostadil 745-65-3 Hormone le endocrine
Tefo:T/T, L/C
Tšimoloho ea Sehlahisoa:China
Boema-kepe:Beijing/Shanghai/Hangzhou
Bokhoni ba tlhahiso:1kg/khoeli
Odara(MOQ): 1g
Lead time:3 Matsatsi a ho sebetsa
Boemo ba polokelo:ka mokotla oa leqhoa bakeng sa lipalangoang, -20 ℃ bakeng sa polokelo ea nako e telele
Lintho tsa sephutheloana:vial, botlolo
Boholo ba sephutheloana:1g/vial, 5/vial, 10g/vial, 50g/botlolo, 500g/botlolo
Lintlha tsa polokeho:UN 2811 6.1/PG 3
Selelekela
Alprostadil, eo hape e bitsoang Prostaglandin E1 kapa PEG1.E fumaneha hohle 'meleng oa lintho tse sebetsang ka biologically, joalo ka e' ngoe ea lelapa la prostaglandin, ke ntho e tsejoang e le endogenous physiologically active.
E ka sebelisoa ka kotloloho ho mesifa e boreleli ea vascular, ho fokotsa methapo ea mali le ho eketsa phallo ea mali, e ka ntlafatsang phallo ea microcirculation.E ka thibela ho bokellana ha platelet le tlhahiso ea thromboxane A2, hammoho le ho thibela atherosclerosis, lipid plaque le ho thehoa ha 'mele oa ho itšireletsa mafung.
E boetse e na le litlamorao tse latelang: ho atolosoa ha methapo e nyane ea mali le methapo ea mali, ho fokotsa khatello ea mali le khatello ea mali.Ho sireletsa lera la platelet le ka thibelang thrombosis.Ho sireletsa myocardium ea ischemic, e ka fokotsang boholo ba infarct ea myocardial.E sebelisoa ho phekola ho hloleha ha pelo hape.E na le ts'ebetso ea diuretic le ts'ireletso ea renal, e ipapisitse le ho atolosoa ha methapo ea mali ea renal ho eketsa phallo ea mali ea renal.Ka tsela ena, e ka tlosa naetrojene e seng protheine, le ho laola tekano ea sodium le metsi.
Tšebeliso ea eona ea bongaka e atile haholo.Joalo ka mathata a lefu la tsoekere, lefu la pelo le ho hloleha ha pelo ho sa phekoleheng.Hape ts'ebeliso maemong a joalo ka lefu la pelo la congenital le rarahaneng le khatello ea mali ea pulmonary, cerebral infarction le lefu le sa foleng la arterial occlusive.Bakeng sa maemo a mang a kang ho se utloe ka tšohanyetso, retinal vein occlusion, kokoana-hloko ea lefu la sebete kapa lefuba le sa foleng, le eona e na le ts'ebetso.E ka sebelisoa ho phekola mafu a mang a kang seso sa duodenal, ho se sebetse hantle ha renal le pancreatitis.E sebelisoa phetisong ea setho.E sebelisoa bakeng sa mafu a mang a kang ho se sebetse ha erectile, ho kenngoa ha mosebetsi le ho tsoa mali ka mor'a ho pepa, hlooho ea hlooho ea botšehali, lumbar disc herniation, postherpetic neuralgia le bronchial asthma.
E tlameha ho sebelisoa ho bakuli ba nang le lefu la pelo, glaucoma, peptic ulcer kapa pneumonia ea interstitial.Ka phello e halefisang ho mothapo, e tla bontša matšoao a ho ruruha joalo ka bofubelu, ho ruruha, mocheso le bohloko, tse ka bakang phlebitis.E tlameha ho emisa ho sebelisoa bakeng sa polokeho ha boemo bo etsahala.
Tlhaloso (USP43)
| Ntho | Tlhaloso |
| Ponahalo | Phofo ea kristale e tšoeu kapa e mosehla hanyane |
| Boitsebiso | IR |
| Masalla ha a tuka | ≤0.5% |
| Moeli oa chromium | ≤0.002% |
| Moeli oa rhodium | ≤0.002% |
| Lintho tse amanang | Prostaglandin A1 ≤1.5% |
| Prostaglandin B1 ≤0.1% | |
| Tšilafalo efe kapa efe ea kantle ea prostaglandin e hlakollang pele ho prostaglandin A1 ≤0.9% | |
| Ho se hloeke ka nako e lekanyelitsoeng ea ho boloka 0.6, e amanang le prostaglandin A1 ≤0.9% | |
| Kakaretso ea litšila ka linako tse lekanyelitsoeng tsa ho boloka 2.0 le 2.3 ≤0.6% | |
| Tšilafalo efe kapa efe e 'ngoe e tsoang kantle ho prostaglandin e tsoang ka mor'a prostaglandin A1 ≤0.9% | |
| Kakaretso ea litšila ≤2.0% | |
| Boikemisetso ba metsi | ≤0.5% |
| Li-solvents tse setseng | Ethanol ≤5000ppm |
| Acetone ≤5000ppm | |
| Dichloromethane ≤600ppm | |
| N-Hexane ≤290ppm | |
| N-Heptane ≤5000ppm | |
| Ethyl acetate ≤5000ppm | |
| Assay (ka motheo oa anhydrous) | 95.0%~105.0% |
