Tulathromycin 217500-96-4 Antibiotic Antifungal
Tefo:T/T, L/C
Tšimoloho ea Sehlahisoa:China
Boema-kepe:Beijing/Shanghai/Hangzhou
Bokhoni ba tlhahiso:400kg / khoeli
Odara(MOQ):25kg
Lead time:3 Matsatsi a ho sebetsa
Boemo ba polokelo:E bolokiloe sebakeng se pholileng, se omileng, mocheso oa kamore.
Lintho tsa sephutheloana:moropa
Boholo ba sephutheloana:25kg / moropa
Lintlha tsa polokeho:Eseng thepa e kotsi
Selelekela
Tulathromycin, ke moriana o thibelang likokoana-hloko o sephara o nang le tšebetso ea antibacteria khahlanong le libaktheria tse ling tsa gram-positive le gram-negative.E ameha ka ho khetheha ho likokoana-hloko tsa mafu a ho hema likhomo le likolobe, tse kang Actinobacillus pleuropneumoniae, Pasteurella haemolyticus, Pasteurella haemorrhagica, histophilus sleep (Haemophilus sleep), Mycoplasma pneumoniae, Haemophilus parasuis, Bordetella bronchiseptica, joalo-joalo.
Litšobotsi tsa pharmacokinetic tsa Tulathromycin ke hore kamora ho tsamaisoa ha lethal dose e le 'ngoe, e kenella ka potlako sebakeng sa ente, khatello ea mali e sebetsang e bolokoa nako e telele, ho felisoa hoa lieha, phallo ea phallo e kholo, bioavailability e phahame, mme mahloriso a lisele tsa peripheral a phahame ho feta a plasma.Kabo e pharalletseng ea lisele le ho kenella hantle ha lisele ke litšobotsi tsa bohlokoa tsa metabolism ea Tulathromycin.Ho bokellana ha lisele tsa 'mele tsa ho itšireletsa mafung le hona ke karolo ea bohlokoa ea Tulathromycin.
Tulathromycin e thibela tlhahiso ea protheine ea baktheria ka ho thibela mokhoa oa phetisetso ea peptide ea baktheria.Ka lebaka la liphoso tse ling tsa bohlokoa tsa erythromycin, batho ba hloka moriana o mong ho e-na le erythromycin ka potlako.Tulathromycin ke mofuta o mocha oa lithibela-mafu tsa macrolide semi synthetic bakeng sa liphoofolo.E na le melemo e mengata, e kang tekanyo e tlaase, tsamaiso ea nako e le 'ngoe, masala a tlaase, liphoofolo tse khethehileng joalo-joalo.Ha e na melemo feela ea lithethefatsi tsa macrolide, empa hape e na le halofo ea bophelo e telele e phahametseng lithibela-mafu tse ling tsa macrolide.Motheong oa molemong oa ho boloka mahloriso a matla a kalafo 'meleng nako e telele, e ka fihlela bacteriostasis e ntle le sterilization.
Kamora ts'ebeliso e pharaletseng ea bongaka, tulathromycin e na le phello e hlakileng ea kalafo ho mafu a phefumoloho a likhomo le likolobe.Re leboha ts'ebetso e ntle ea antibacterial ea Tulathromycin joalo ka tšebeliso e nyane, halofo ea bophelo bo bolelele le tsamaiso ea nako e le 'ngoe, e ka sebelisoa haholo.
Tulathromycin e matla ho feta li-macrolides tse sebelisoang haholo 'marakeng hajoale, joalo ka tylosin, tilmicosin le florfenicol.E nang le lisebelisoa tse kholo tse ka khonehang.
Ho lokela ho lefshoa hore Tulathromycin e batla e bolokehile, ha e na carcinogenicity, teratogenicity le genotoxicity.E ke ke ea susumetsa phetoho ea liphatsa tsa lefutso, empa e ka hlahisa cardiotoxicity.Ho hlokahala ho latela keletso ea bongaka ba liphoofolo.
Tlhaloso (In House Standard)
| Ntho | Tlhaloso |
| Ponahalo | Phofo e tšoeu kapa e batlang e le tšoeu |
| Solubility | E qhibiliha ka bolokolohi ho methanol, acetone, le methyl acetate, e qhibilihang ka har'a ethanol. |
| Potoloho e khethehileng ea optical | -22 ° ho -26 ° |
| Boitsebiso | HPLC: nako ea ho boloka tlhoro e kholo ea chromatogram ea boitokisetso ba tlhahlobo e lumellana le e ho chromatogram ea tokiso e makatsang e fumanoeng joalo ka ha ho boletsoe tlhahlobong. IR: Pono ea IR e lumellana le CRS |
| Metsi | ≤2.5% |
| Masalla ha a tuka | ≤0.10% |
| Litšepe tse boima | ≤20ppm |
| Ntho e amanang le yona | Ho se hloeke hohle ≤6.0% Ho se hloeke ha motho ka mong ≤3.0% |
| Endotoxin ea baktheria | <2 EU |
| Assay (ntho e se nang metsi) | 95%-103% |
| Mokelikeli o setseng | N-Heptane≤5000ppm Dichloromethane ≤600ppm |
| Tlhahlobo | Litaba tsa C41H79N3O12: 95% -103% (Ho Ntho ea Anydrous) |
