Litaba

Tekanyetso ea taolo ea boleng ba tlhahiso ea meriana (GMP) eo re e tloaetseng, ho kenyelletsoa butle-butle ha EHS ho GMP, ke mokhoa o akaretsang.

Ntho ea mantlha ea GMP, ha e hloke feela sehlahisoa sa ho qetela ho fihlela litekanyetso tsa boleng, empa hape le ts'ebetso eohle ea tlhahiso e tlameha ho fihlela litlhoko tsa GMP, tsamaiso ea theknoloji ea ts'ebetso, tsamaiso ea palo ea batch / batch, tlhahlobo le tlhahlobo ea tekanyo ea thepa, tsamaiso ea bophelo bo botle, taolo ya boitsebahatso, taolo ya ho kgeloha e le sepheo.Ho ts'ebetso efe kapa efe e amang lintlha tse ka sehloohong tsa boleng ba sehlahisoa (ring-machine material ring) ho nka mefuta eohle ea mehato e sebetsang ho thibela tšilafalo le tšilafalo ea sefapano, pherekano le phoso ea batho, ho netefatsa polokeho ea tlhahiso ea lithethefatsi, ho netefatsa boleng ba tlhahiso ea lithethefatsi. lithethefatsi.Ka Mots'eanong 2019, WHO e phatlalalitse Likarolo tsa Tikoloho tsa Mekhoa e Metle ea Tlhahiso: Menahano bakeng sa Baetsi le Bahlahlobi mabapi le thibelo ea ho hanyetsa lithibela-mafu, ho kenyeletsoa litšila le kalafo ea metsi a litšila joalo ka libaka tsa tlhahlobo tsa GMP.Taba ea ts'ireletso ea basebetsi le eona ho lumeloa hore e tla ngoloa ho GMP e ncha.Ts'ireletso ea Occupational exposure level (OEB), e lokela ho lebisa tlhokomelo ea likhoebo tsa meriana!

Likotsi tsa mosebetsi tse bakoang ke metsoako e sebetsang ea meriana (API) ke lintlha tsa bohlokoa le tse thata tsa ho thibela likotsi tsa mosebetsi le taolo ea taolo likhoebong tsa meriana.Ho itšetlehile ka kotsi, lithethefatsi tse ncha ka kakaretso le lithethefatsi tse sebetsang haholo, tse kang lithethefatsi tsa kankere le penicillin, li hohela tlhokomelo e eketsehileng, empa lithethefatsi tse tloaelehileng ha li hohele tlhokomelo e ngata lapeng le linaheng tse ling.Ntho e thata ka ho fetisisa ke hore boleng ba "industrial hygiene (IH)" ea motsoako o sebetsang o thata ho tseba 'me o hloka ho qala ho tloha ho toxicology le kliniki.Boemo ba taolo ea OEB hangata bo hlophisoa ho latela liphetho tsa lipotso tsa MSDS tsa metsoako.Haeba u sebelisa litlhare tse ncha, ho ka 'na ha hlokahala hore u sebelise chelete ea hao le matla a hao ho etsa liteko tse amanang le tšebetso e kopanetsoeng;Bakeng sa lithethefatsi tse tloaelehileng, meeli le limaraka tsa OEL/OEB hangata li ka fumanoa ka ho botsa lintlha tsa MSDS tsa motsoako.Mehato e amanang le taolo ea boenjiniere e arotsoe ka kakaretso ka: 1. Ts'ebetso e bulehileng;2. Ts'ebetso e koetsoeng;3. Phepelo ea moea ka kakaretso;4. Mokhathala oa sebaka;5. Phallo ea laminar;6. Motho ea itšehlang thajana;7. Alpha beta valve, joalo-joalo Ha e le hantle, bohle re tseba tsena ho ea ka pono ea GMP, empa ntlha ea ho qala ho nahanoa ka kakaretso e tsoa ponong ea ho thibela tšilafalo le tšilafalo ea sefapano, 'me ka seoelo ho tloha ponong ea bohloeki ba indasteri.

Likhoebo tsa lehae tsa meriana li lokela ho matlafatsa ts'ireletso ea basebetsi ba EHS le ho hlahisa lisebelisoa tsa tlhahiso tse tsamaisanang le maemo a API OEB.Ho bohlokoa ho ithuta ho tsoa ho hore barekisi ba bang ba lisebelisoa tsa Europe le Amerika ba sebelitse hantle ts'ireletso ea mosebetsi bakeng sa basebetsi ba bona, ho hloka lifaele tse tsamaellanang tsa MSDS le ts'ireletso e ts'oanang e bolela litokomane tsa ho lokisa bakeng sa lihlahisoa tsa tlhahlobo.Nakong e fetileng, ha likhoebo tsa malapeng tsa meriana li etsa lihlahisoa tse fapaneng tse kang anesthesia e ntle le ho ntša chefo, tšireletso ea OEB e ne e le sieo, e leng se ileng sa etsa hore bophelo bo botle ba basebetsi ba pele bo amehe.Tlas'a maemo a hore tlhokomeliso ea molao ea basebetsi e ile ea matlafatsoa butle-butle, likhoebo li ne li ke ke tsa qoba boikarabelo ba likotsi tse amanang le mosebetsi.

Ka tlhahlobo ea kotsi ea API, ho fanoa ka mokhoa oa ho bala oa occupational exposure limit (OEL), ho hlahisoa tsamaiso ea API hazard classification system PBOEL, 'me melao e akaretsang e lokelang ho lateloa bakeng sa mehato ea thibelo le taolo e behoa pele.Nakong e tlang, re tla sekaseka leano la taolo ka botebo.Lula u mametse!