Litaba

Peptide ea koporo e boetse e bitsoaGHK-cuke motsoako o entsoeng ka motsoako oatripptide-1le ion ea koporo.Lintlha tsa lipatlisiso li bontša hore koporo 'meleng oa phoofolo e phetha karolo ea bohlokoa ka litsela tse fapaneng, haholo-holo ka tšusumetso ea koporo ho li-enzyme tsa antioxidant.Ho na le li-enzyme tse ngata tsa bohlokoa 'meleng le letlalong la motho tse hlokang li-ion tsa koporo.Li-enzyme tsena li na le karolo ho thehoeng ha lisele tse kopanyang, anti-oxidation le ho phefumoloha ha lisele.Koporo e boetse e phetha karolo ea pontšo, e ka amang boitšoaro le metabolism ea lisele.Ha Copper peptide e qhibiliha ka metsing, e bonts'a 'mala o moputsoa oa borena o bitsoang Blue Copper peptide tšimong ea indasteri.

Patlisiso e bonts'a hore Copper peptide e na le melemo e mengata bakeng sa tlhokomelo ea letlalo, e nang le ts'ebeliso e kholo indastering ea litlolo.

1. Karolo ea peptide ea koporo ho lokisoeng ha letlalo

Patlisiso e bonts'a peptide ea koporo e fetola metalloproteinase tse fapaneng ts'ebetsong ea kaho ea letlalo la likhoto.Mosebetsi oa enzyme o khothalletsa ho senyeha ha liprotheine tsa matrix tsa extracellular, tse ka leka-lekanya ho senyeha ha liprotheine tsa extracellular matrix (ECM protheine) le ho thibela tšenyo e feteletseng ea letlalo.Peptide ea koporo e eketsa proteoglycan ea mantlha.Mosebetsi oa proteoglycan ena ke ho thibela ho thehoa ha maqeba le ho fokotsa boemo ba phetoho ea kgolo (TGF beta), e leng ho eketsang maqeba ka ho laola kopano ea collagen fibrils.

2. E susumetsa tlhahiso ea collagen

Liteko tse ngata li netefalitse hore tripeptide-1 e susumetsa tlhahiso ea collagen, glycosaminoglycan e khethiloeng le protheine e nyane ea glycan deproteinization.Ho phaella moo, e ka boela ea laola motsoako oa metalloproteinase e amanang le eona.Tse ling tsa li-enzyme tsena li tla potlakisa ho bola ha liprotheine tsa matrix tsa extracellular, ha tse ling li ka thibela tšebetso ea protease.Sena se bontša hore peptide ea koporo e ka laola boemo ba protheine letlalong.

3. Anti inflammatory le antioxidant

Ho ile ha fumanoa hore peptide ea koporo e thibela ho ruruha ka ho fokotsa maemo a li-cytokine tsa ho ruruha tse kang TGF-beta le TNF-a karolong e boima.Tripeptide-1 e boetse e fokotsa tšenyo ea oxidative ka ho laola boemo ba tšepe le ho tima lihlahisoa tse chefo tsa mafura a acid lipid peroxidation.

4. Khothalletsa ho folisa maqeba

Lithuto tse ngata tsa liphoofolo li netefalitse hore peptide ea koporo e putsoa e na le bokhoni ba ho folisa maqeba.Tekong ya mmutla, peptide e putswa ya koporo e ka potlakisa phodiso ya maqeba, ya kgothalletsa angiogenesis, le ho eketsa dikahare tsa di-antioxidant enzymes mading.

5. Khutlisa mosebetsi oa lisele tse senyehileng

Li-fibroblasts ke lisele tse ka sehloohong tsa pholiso ea maqeba le ho nchafatsa lisele.Ha li kopane feela ka likarolo tse fapaneng tsa matrix a extracellular, empa hape li hlahisa palo e kholo ea lintlha tsa kholo.Phuputso e entsoeng ka 2005 e bontšitse hore tripeptide-1 e ka tsosolosa ts'ebetso ea li-fibroblasts tse nang le mahlaseli.

Peptide ea koporo ke mofuta oa polypeptide e nang le thepa e thibelang botsofali le ho lokisa.E ke ke ea khothalletsa tlhahiso ea mofuta oa I, IV le VII collagen feela, empa hape e khothalletsa mosebetsi oa collagen synthesis cell fibroblast, e leng motsoako o babatsehang haholo oa ho thibela botsofali.

Mabapi le ho lokisoa, peptide ea koporo e ka sireletsa li-fibroblasts tse susumelitsoeng ke UV, ea ntlafatsa mosebetsi oa bona, ea fokotsa secretion ea MMP-1, e sebetsana ka katleho le mabaka a ho ruruha a hlahisoang ke kutlo, ho boloka tšireletso ea letlalo e senyehile ka lebaka la ts'usumetso ea ka ntle, 'me e na le anti-anti. alejiki le matla a thobang.Peptide ea koporo e kopanya khahlanong le botsofali le ho lokisoa, e leng ntho e sa tloaelehang haholo ho lisebelisoa tsa hona joale tse thibelang botsofali le ho lokisa.